Multi-Focus Imaging using Local Focus Estimation and Mosaicking

Dmitry Fedorov, Baris Sumengen, B. S. Manjunath
Center for Bio-Image Informatics
Department of Electrical and Computer Engineering
University of California, Santa Barbara, CA 93106.
email: {fedorov,sumengen,manj} [at]


We propose an algorithm to generate one multi-focus image from a set of images acquired at different focus settings. First images are registered to avoid misalignment if needed. Then, best focus is estimated in overlapping local neighborhoods. These neighborhoods are then seamlessly mosaicked back together. Our approach is presented for light microscopy and hand held consumer cameras and demonstrates high quality results, robustness to misalignment, and computational efficiency.
[PDF] [BibTex]
Dmitry Fedorov, Baris Sumengen and B. S. Manjunath,
IEEE International Conference on Image Processing 2006 (ICIP06), Atlanta, GA USA, Oct. 2006.
Node ID: 425 , DB ID: 227 , Lab: VRL , Target: Proceedings