USE OF IMPERFECTLY SEGMENTED NUCLEI IN THE CLASSIFICATION OF HISTOPATHOLOGY IMAGES OF BREAST CANCER
Abstract
Many features used in the analysis of pathology imagery are inspired
by grading features defined by clinical pathologists as important for
diagnosis and characterization. A large majority of these features are
features of cell nuclei; as such, there is often the desire to segment
the imagery into individual nuclei prior to feature extraction and further
analysis. In this paper we present an analysis of the utility of
imperfectly segmented cell nuclei for classification of H&E stained
histopathology imagery of breast tissue. We show the object- and
image-level classification performance using these imperfectly segmented
nuclei in a benign versus malignant decision. Results indicate
that very good classification accuracies can be achieved with
imperfectly segmented nuclei and further that perfect nuclei segmentation
does not necessarily guarantee better classification accuracy.
“USE OF IMPERFECTLY SEGMENTED NUCLEI IN THE CLASSIFICATION OF HISTOPATHOLOGY IMAGES OF BREAST CANCER”,
Proc. of IEEE ICASSP, pp. 666-699, Dallas, Texas, Mar. 2010.
Node ID: 553 ,
DB ID: 362 ,
Lab: VRL ,
Target: Conference